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Instead of processing one object at a time, our software considers all possible displacements of all targets simultaneously. This allows to return globally optimal tracks.

Using this technology, targets that are very similar to each others, densely packed, or very mobile can also be handled. This is critical in many applications, from tracking fluorescent proteins in vivo, to mapping fluid flows.

Based on iterative fitting of Gaussian profiles on particles, Super-resolution down to 0.01 pixels is possible.
© Semasopht 2002 - 2008 info@semasopht.com
MORE PUBLICATIONS USING DIATRACK

Vallotton P. Quantitative analysis of time-lapse sequences. Bioworld 1-2004.

Vallotton P., Ponti A., Salmon E.D., Waterman-Storer C., and Danuser G. Recovery, visualization, and analysis of actin and tubulin polymer flow in live cells: A fluorescent Speckle Microscopy study. Biophys. J. 2003, 85:1289-306

Vallotton P, Gupton SL, Waterman-Storer CM, Danuser G. Simultaneous mapping of filamentous actin flow and turnover in migrating cells by quantitative fluorescent Speckle Microscopy. PNAS 2004, jun 21.

Shuo-Chien Ling , Peter S. Fahrner , William T. Greenough , Vladimir I. Gelfand. Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein, PNAS 2004; 101: 17428-17433

Vallotton P, Danuser G, Bohnet S, Meister JJ, Verkhovsky AB.Tracking retrograde flow in keratocytes: news from the front. Mol Biol Cell. 2005 Mar;16(3):1223-31

Deacon SW, Nascimento A, Serpinskaya AS, Gelfand VI. Regulation of Bidirectional Melanosome Transport by Organelle Bound MAP Kinase. Curr Biol. 2005 Mar 8;15(5):459-63.

Trelles-Sticken E, Adelfalk C, Loidl J, Scherthan H. Meiotic telomere clustering requires actin for its formation and cohesin for its resolution. J Cell Biol. 2005 Jul 18;170(2):213-23.

Traffic. 2007 Jul;8(7):867-82. Rab18 inhibits secretory activity in neuroendocrine cells by interacting with secretory granules
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